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Monday, September 12, 2022

Serum Protein: Test Overview, Indications, Abnormal levels, Nursing Implication by Nurses Note

 Serum Protein



Serum protein gives a measure of the total amount of albumin and globulins in the plasma. Proteins form a major component of blood, skin, hair, nails, and internal organs. 

NORMAL RANGE OF SERUM PROTEIN: 6 to 8 g/dL 

INDICATIONS OF SERUM PROTEIN

The patient's overall nutritional status is obtained by the assessment of serum protein levels, especially if the patient comes with a history of unknown causes of significant weight loss. This test is also indicated to assess liver disorders, renal disorders, and bone marrow disorders as part of liver function tests, and to investigate the cause of oedema. 

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INTERPRETATION 

Protein is responsible for regulating plasma oncotic pressure and is necessary for the formation of many hormones, enzymes, and antibodies. 

INCREASED LEVELS 

chronic infection, Crohn’s disease, hepatitis B, hepatitis C, Addison’s disease, autoimmune collagen disorders, amyloidosis, dehydration, human immunodeficiency virus, multiple myeloma. 

DECREASED LEVELS 

Kidney disorder, liver disease, severe malnutrition, agammaglobulinemia, bleeding, celiac disease, extensive burns, inflammatory bowel disease. 

INTERFERING FACTORS

Drugs like allopurinol, asparaginase, azathioprine, chlorpropamide, cisplatin, dapsone, dextran, estrogens, ibuprofen, progesterone, acute and chronic inflammations and decreased liver synthesis, albumin values normally decrease in third trimester of pregnancy. 


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NURSING IMPLICATIONS 

Make a list of medications the patient is taking, Inform the patient about the test procedure. No fluid or food restrictions are required before the procedure. 


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